Thank you for providing details and help on this issue. I know how frustrating it can be, really do, it is awful. With my Windows 10 Wacom pen setup, I can reproduce the problem and am providing logs to engineering. Rarely had my very basic (Microsoft) mouse to show the problem, but have seen it happen once or twice.
My steps are, brush tool, using (hand) Spacebar and ALT for selecting color, switching brushes etc. However, I have even seeing after just opening files. I use Adobe Bridge frequently, not sure if that is even part of it but thought I would mention it.
Please know we have been working on it.
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